Effects of Physical Exercise on Lipid and Inflammatory Profile of Women Using Combined Oral Contraceptive: A Cross-Over Study

Abstract Background: The use of combined oral contraceptives (COC) is a risk factor for atherosclerotic disease, and physical exercise can minimize this condition. Objective: To verify if high intensity interval training (HIIT) promotes changes in the lipid and inflammatory profile of women using COC. Methods: Sequential crossover study with women aged 20-30 years, classified as irregularly active by the international physical activity questionnaire (IPAQ), when using COC. A physical-clinical assessment was performed with anthropometric measurements, VO2max, and analysis of lipid and inflammatory profile. Participants were divided into 2 groups: the initial intervention group (GII), which began practicing HIIT for 2 months, and the posterior intervention group (GIP), which remained inactive for the same period. The GII and GIP would then alternate their conditions. The collected data was divided into: Initial moment (IM), post-exercise moment (PEM) and post-inactivity (PIM). The statistical analyses were performed using the Statistical Package for the Social Sciences, adopting a significance level of p <0.05 . Results: Twelve women were evaluated. After crossing the GII and GIP data, there was a difference in the C-reactive protein values between the IM of 4 (1.6-6.3 mg/dL) vs. PEM 2 (1.5-5 mg/dL); as well as between the PEM vs. the PIM= 4 (1.5-5.8 mg/dL), with a p -value = 0.04 in the comparisons. There was no change between the "moments" of the lipid profile, although it was possible to notice a reduction in resting HR and an increase in indirect VO2max. Conclusion: The HIIT program was able to reduce the inflammatory profile, but it did not alter the lipid profile of irregularly active women using COC.

Eficácia de um programa de condicionamento físicointervalado sobre a tolerância à caminhada em umindivíduo com doença arterial obstrutiva periférica / Effectiveness of a physical conditioning program on walk tolerance in an individual with peripheral arterial obstructive disease

A doença arterial obstrutiva periférica (DAOP) afeta 20% dapopulação idosa atingindo mais homens do que mulheres. Dentre ossintomas a claudicação intermitente é a manifestação mais comum,resultando em limitação significante da caminhada. O objetivo desterelato de caso foi avaliar a eficácia de um programa de condicionamentoem esteira ergométrica sobre a tolerância à caminhada (TC)de um indivíduo com DAOP. Indivíduo WCF, sexo masculino,74 anos, apresentava obstrução total de artéria superficial da coxae 95% de obstrução arterial em poplítea e tibial anterior, todas emmembro inferior direito, identificadas por arteriografia. Foi submetidoa um Teste de Tolerância Máxima à Caminhada (TTMC) emesteira ergométrica a 2,0 km/h e posteriormente a um programa decondicionamento realizado três vezes por semana em sete séries de80% do TTMC, com um minuto de descanso, a 2,0 km/h durantequatro meses. Após esse período realizou-se novo TTMC. Foi observadoque a TC aumentou 663%, ocorrendo também diminuiçãodo número de paradas para descanso nos percursos habituais. Osresultados sugerem que o treinamento em esteira foi eficiente namelhora da TC nesse indivíduo...

Peripheral arterial obstructive disease (PAOD) affects 20% of theelderly population and increases the risk of cardiovascular disease.Most frequent symptom of PAOD is intermittent claudication,which depends on the discrepancy between supply and demand ofoxygen required by the muscles during walking. The purpose of thiscase study was to evaluate the efficacy of a conditioning programon a treadmill, on the walking tolerance (WT) of an individualwith PAOD. WCF, male, 74 years, presented total superficial femoralartery occlusion and 95% of popliteal arterial occlusion andanterior tibial artery, all in the right leg, identified by angiography.He underwent a test in the treadmill at 2.0 km/h to assess maximalwalking tolerance (MWTT) and then performed a conditioningprogram three times per week in seven sets of 80% of MWTT intreadmill, with one minute rest, 2.0 km/h for four months. Afterthis period MWTT was performed again. It was observed that WTincreased 663%, and the number of rest intervals stops decreasedduring the daily walks. The results suggest that treadmill trainingwas effective in improving WT in this individual...